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Table 3 Tcorr performance using either the four most intensive y ions only, or the four most intense ions observed (regardless of b or y ion status)

From: Critical Evaluation of Product Ion Selection and Spectral Correlation Analysis for Biomarker Screening Using Targeted Peptide Multiple Reaction Monitoring

Size of candidate peptide pool

ROC area

4 y ions

4 b/y ions

10

0.674

0.755

100

0.228

0.356

1,000

0.009

0.144

  1. The ROC area data were based on the DIMS spectrum library of 384 peptides