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Table 2 The sequence for the citrullinated peptide along with other fragments for which high-resolution MS and MS/MS spectra were obtained

From: Targeted Synovial Fluid Proteomics for Biomarker Discovery in Rheumatoid Arthritis

  1. The dM indicates the nominal mass difference between the expected and observed mass for the unmodified precursor ion. Possible sites of post-translational modification are indicated in red. Only citrullination of the Arg residue is consistent with the observed mass values and the failure of trypsin to cleave at that site
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Clinical Proteomics

ISSN: 1559-0275