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Fig. 3 | Clinical Proteomics

Fig. 3

From: Adiponectin Receptor-1 C-Terminal Fragment (CTF) in Plasma: Putative Biomarker for Diabetes

Fig. 3

AdipoR1 receptor. The AdipoR1 receptor is an atypical seven-transmembrane domain, G protein-coupled receptor. As shown, the AdipoR1 receptor is unique in that the C-terminal end is located on the extracellular side of the membrane and N-terminal on the intracellular side. AdipoR1 C-terminal fragments of interest are highlighted including the 19-, 25-, 32-, and 35-amino acid fragments: 19-aa fragment represents target for polyclonal antibody, 25-aa fragment represents the target for the monoclonal antibody, 32-aa fragment represents the clinical fragment captured by the monoclonal AdipoR1 immunoaffinity, and 35-aa fragment represents the polyclonal AdipoR1 immunoaffinity captured fragment

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