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Table 2 Inter-disease trends: metabolism-related proteins

From: The effect of disease on human cardiac protein expression profiles in paired samples from right and left ventricles

 

Log2fold diff. vs. RVCAD

Protein [Swiss-Prot accession number]

LVCAD

RVAVS

LVAVS

Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial [P55809]

0.14

0.63*#

0.37

UTP--glucose-1-phosphate uridylyltransferase [Q16851]

0.03

0.47*#

0.37

ADP/ATP translocase 2 [P05141]

0.11

0.42*#

0.38

Acyl-coenzyme A thioesterase 9, mitochondrial [Q9Y305]

−0.05

0.39*#

0.29

Dihydrolipoyl dehydrogenase, mitochondrial [P09622]

0.12

0.37*#

0.28

Cytochrome c [P99999]

0.05

0.31*#

0.24

Phosphoglucomutase-1 [P36871]

−0.02

0.15*#

0.07

Acetyl-coenzyme A synthetase, cytoplasmic [Q9NR19]

0.07

−0.20*#

−0.17

Medium-chain specific acyl-CoA dehydrogenase, mitochondrial [P11310]

0.09

0.42*

0.34

D-beta-hydroxybutyrate dehydrogenase, mitochondrial [Q02338]

0.20

0.41*

0.34

Enoyl-CoA hydratase, mitochondrial [P30084]

0.15*

0.38*

0.26

Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial [P10515]

0.12

0.35*

0.29

Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial [P36957]

0.10

0.34*

0.26

Fumarate hydratase, mitochondrial [P07954]

0.12

0.34*

0.25

Amine oxidase [flavin-containing] B [P27338]

0.06

0.25*

0.13

ADP/ATP translocase 1 [P12235]

0.13

0.24*

0.15

Electron transfer flavoprotein subunit beta [P38117]

0.08*

0.22*

0.14

Fatty acid-binding protein, heart [P05413]

0.03

0.21*

0.18

Malate dehydrogenase, cytoplasmic [P40925]

0.05

0.20*

0.13

Pyruvate dehydrogenase protein X component, mitochondrial [O00330]

0.05

0.34#

0.27

Glycogen phosphorylase, brain form [P11216]

−0.01

0.29#

0.23

Phosphatidate cytidylyltransferase 2 [O95674]

0.01

0.26#

0.17

Triosephosphate isomerase [P60174]

0.05

−0.04#

−0.03

  1. Proteins (metabolism-related) significantly altered in one of the AVS ventricles compared to either the left or right ventricle of CAD group and had a similar trend in the adjacent AVS ventricle. Data are presented as log2 fold difference compared to the right ventricle of the CAD patients.
  2. *P < 0.05 vs. RVCAD and #P < 0.05 vs. LVCAD.
  3. Fold diff. = Fold difference.
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Clinical Proteomics

ISSN: 1559-0275