Table 3 Coefficient of variation (CV) of protein abundance as evaluated on the 10 HPS samples in Study I
Protein (HUMAN) | CV (%) | CV reduction (%) | |||||
|---|---|---|---|---|---|---|---|
InteQuan | SISQuan | EPN | Raw | SISQuan-InteQuan | EPN-SISQuan | Raw-EPN | |
KIT | 8.8 | 9.6 | 15.0 | 24.1 | 0.8 | 5.4 | 9.2 |
FRIL | 16.8 | 25.2 | 21.9 | 28.0 | 8.4 | -3.3 | 6.1 |
COIA1 | 12.6 | 17.8 | 20.3 | 27.2 | 5.2 | 2.5 | 7.0 |
PRDX1 | 10.7 | 15.4 | 12.1 | 19.7 | 4.7 | -3.3 | 7.6 |
TENX | 11.1 | 13.6 | 9.6 | 20.2 | 2.5 | -4.0 | 10.6 |
ENPL | 13.1 | 18.9 | 6.9 | 19.1 | 5.8 | -12.0 | 12.2 |
GRP78 | 6.8 | 11.4 | 16.7 | 22.5 | 4.5 | 5.3 | 5.8 |
BGH3 | 5.0 | 12.3 | 16.7 | 23.3 | 7.3 | 4.4 | 6.5 |
ALDOA | 6.6 | 13.6 | 17.7 | 28.6 | 7.0 | 4.1 | 11.0 |
GGH | 6.9 | 7.1 | 6.8 | 17.2 | 0.2 | -0.3 | 10.3 |
CD14 | 4.1 | 8.0 | 21.1 | 31.8 | 3.8 | 13.1 | 10.7 |
LG3BP | 8.8 | 13.0 | 8.8 | 19.4 | 4.2 | -4.2 | 10.6 |
TSP1 | 11.6 | 18.3 | 19.6 | 22.5 | 6.7 | 1.3 | 2.8 |
IBP3 | 5.7 | 11.6 | 5.7 | 12.4 | 5.9 | -5.9 | 6.6 |
TETN | 9.9 | 17.8 | 19.6 | 21.7 | 7.9 | 1.8 | 2.1 |
ISLR | 10.0 | 9.1 | 13.5 | 20.5 | -0.9 | 4.4 | 7.0 |
Median | 9.3 | 13.3 | 15.9 | 22.1 | 4.9 | 1.6 | 7.3 |
P value (paired sign test) |  |  | 5.2 × 10 -04 | 0.80 | 3.1 × 10 -05 | ||