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Table 8 Proteomic changes in the serum of GH deficient patients

From: The impact of growth hormone on proteomic profiles: a review of mouse and adult human studies

Study design

Differentially expressed proteins (gene abbreviations)

GH deficiency

Serum proteomics of 8 GH deficient patients (3 females and 5 males), before and 3 months after GH replacement therapy [172]

Increased

Decreased

IGF-I

APOA1

HP (5 isoforms)

  1. Proteomic changes in the plasma of GH deficient patients, showing increases in IGF-I and APOA1 alongside decreases in several HP isoforms