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Fig. 1 | Clinical Proteomics

Fig. 1

From: Tailored therapeutic decision of rheumatoid arthritis using proteomic strategies: how to start and when to stop?

Fig. 1

Serum proteome in the therapeutic decision of rheumatoid arthritis. a The serum proteome results from the interaction between inflamed joints and various tissues, such as liver, adipose tissue, connective tissues, and circulating blood cells. Mɸ macrophages, DCs dendritic cells, DAMPs danger-associated molecular pattern molecules, ECM extracellular matrix. b Serum proteins can aid in clinical decision-making in different stages of RA treatments. The trapezoid shadow represents the period of treatment administration followed by gradual tapering. The dashed line depicts the changes in disease activity in patients who achieved remission with treatments but relapsed after treatment withdrawal. The solid line illustrates the changes in disease activity in non-responders

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