Fig. 2

Autoantibodies in the prediction of treatment responses. a The relationship between the single positivity of antibodies and the treatment outcomes in RA patients, with red lines indicating a positive association, double dashed green lines indicating an inconsistent association, and dashed grey lines indicating no significant association. b The coexistence of antibodies associated with favorable treatment responses is illustrated by connected areas, while the combination of antibodies associated with unfavourable responses is depicted by dashed lines. The references are provided in Additional file 2: Table S2. Anti-PAD4 anti-peptidylarginine deiminase 4, anti-Pg anti-Porphyromonas gingivalis, anti-CarP anti–carbamylated protein, anti-MAA anti-malondialdehyde-acetaldehyde adducts, anti-hnRNP-DL anti-heterogeneous nuclear ribonucleoproteins-D-like protein, anti-CENPF anti-centromere protein F, anti-MCV anti-mutated citrullinated vimentin, AAPA anti-acetylated peptide antibodies