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Table 3 Model of EDSS score as a function of time and protein tertile (low, medium high) using generalized estimating equations

From: Cerebrospinal fluid camk2a levels at baseline predict long-term progression in multiple sclerosis

Parameter

Estimate

Robust S.E.

95% CI

p-value

Intercept: Low

2.61

0.54

(1.56, 3.67)

< 0.001

Slope: Low

0.15

0.04

(0.08, 0.23)

< 0.001

Tertile Effects

   

0.11

Intercept: Middle vs. Low

-1.01

0.56

(-2.10, 0.09)

0.07

Intercept: High vs. Low

-0.491

0.66

(-1.79, 0.81)

0.46

Tertile x Time Effects

   

0.09

Slope: Middle vs. Low

-0.08

0.05

(-0.17, 0.01)

0.09

Slope: High vs. Low

-0.12

0.06

(-0.24, -0.01)

0.04