Fig. 1
From: Proteomic analysis identifies subgroups of patients with active systemic lupus erythematosus
Cluster analysis of proteins in 223 patients with active SLE. A t-distributed stochastic neighbour embedding (t-SNE) plot of the 6 clusters following hierarchal clustering. Each point represents a single patient allocated to one of n = 6 clusters based on the plasma proteome alone. B Heatmap of the 6 clusters showing only those proteins which were significantly different in at least 1 cluster. Colour shows the Z-score with increased levels in red and decreased levels in blue. C Canonical pathways that are predicted to be activated or supressed in more than one cluster. The arrows show the direction (up = activation, down = suppression)