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Table 4 Logistic regression model for active renal disease across the whole cohort

From: Proteomic analysis identifies subgroups of patients with active systemic lupus erythematosus

Outcome

Clinical model

AUC ROC

3 proteins alone

AUC ROC

Clinical model + 3 proteins

AUC ROC

p-value (clinical model vs clinical model + proteins)

Active renal disease (BILAG A or B)

0.7346

0.6735

0.7784

0.0617

Biopsy-proven nephritis

0.8115

0.6947

0.8600

0.0830

Proteinuria (ACR > 70)

0.6691

0.6690

0.7208

0.2162

  1. Clinical model comprises: age, gender, ethnicity, high dsDNA, low C3 and/or C4
  2. Proteins: SND1, AGL, MZ