Fig. 1
From: Proteomic analysis of 92 circulating proteins and their effects in cardiometabolic diseases
a Distribution of the number of pQTLs per protein. We observe a range of 1–2 pQTLs per protein for 23 proteins and 19 + pQTLs for each of two proteins. b Minor allele frequency (MAF) versus absolute value of effect size. As the MAF increases, size of the effect tends to increase. c. Distance from variant to transcription start site of protein (TSS) versus negative log P. Variants plotted here include all SNPs on the same chromosome as the coding region of the protein. The most statistically significant pQTLs are closest to the TSS. d pQTL position versus location of protein coding gene