Fig. 2
From: Proteomics of prostate cancer serum and plasma using low and high throughput approaches
FAIMS parameters optimization. (A) and (B) effect of varying the collision energy (CE) on Peptide-Spectrum Matches (PSM). CE is adjusted to control the extent of fragmentation or dissociation of the ions. By increasing or decreasing the collision energy as a percentage of the maximum, one can influence the type and extent of fragmentation that occurs. (C) effect of varying the fit filter settings on PSM identification rates. Fit filter is a method used to select precursor ions with a defined precursor specificity. It does so by comparing the observed isotopic envelope (the distribution of isotopes for a given ion) to a theoretical isotopic envelope