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Fig. 1 | Clinical Proteomics

Fig. 1

From: Neat plasma proteomics: getting the best out of the worst

Fig. 1

Impact of dia-PASEF acquisition method optimization. A Number of identified protein groups and precursors across 33 neat plasma samples (mean ± standard deviation) using “Narrow” and “Broad” methods for nE and Evosep liquid chromatography systems. Welch Two Sample t-test are included for each comparison with respective p-value. B Venn diagram and mean LFQ intensity distribution of the protein groups relationships between “Narrow” and “Broad” methods. C Global ion map (left panel), ion mobility distribution of precursors from “Narrow” and “Broad” method and corresponding Venn Diagram of their respective precursors (right panel). D Ion mobility (left panel) and molecular weight (right panel) distribution of the peptides exclusively found in the “Broad” method and in common between “Broad” and “Narrow” methods

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