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Fig. 4 | Clinical Proteomics

Fig. 4

From: A Technical Assessment of the Utility of Reverse Phase Protein Arrays for the Study of the Functional Proteome in Non-microdissected Human Breast Cancers

Fig. 4

The reproducibility of clinically important breast cancer protein biomarkers detected by reverse phase protein array (RPPA) despite intratumoral heterogeneity. In two cohorts of separate sections derived from each of 49 non-microdissected hormone receptor-positive breast cancers, high expression of cyclin B1 and of p53 proteins as determined using RPPA (>log mean centered cutoff of 0) was associated with short disease-free survival times

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