Figure 2From: Identification of a seven glycopeptide signature for malignant pleural mesothelioma in human serum by selected reaction monitoringQuantification of serum mesothelin. (A) Correlation between the quantification of serum mesothelin by SRM assay technology (peptide KWDVTSLETLK) or by ELISA (Mesomark®) among 75 subjects (23 MPM = red dots, 26 HD = blue dots, 26 NSCLC = green dots) (Additional file 3: Table S2). Reported is the Spearman’s rank correlation coefficient (P < 0.05 is considered significant). Dashed line denotes best fit as calculated by linear regression (y = 8.1 + 0.82x). (B) Serum levels of mesothelin assessed by ELISA (Mesomark®) or by SRM assay technology (peptide KWDVTSLETLK) in the groups of MPM, HD and NSCLC of the 75 subjects (23 MPM, 26 HD, 26 NSCLC) (Additional file 3: Table S2). Significant differences of mean levels between the groups are assessed using the Mann-Whithney test. P-values are two-tailed and considered significant if < 0.05. Boxes report 25th and 75th percentile. Crosses inside the boxes indicate means and lines indicate medians. Whiskers indicate minimal and maximal values.Back to article page