Figure 1From: Technology platform development for targeted plasma metabolites in human heart failureAn overview of existing workflow for sample preparation in the studies of human plasma metabolomics. Human plasma is first deproteinized with organic solvent, in which proteins are precipitated (step 1). The metabolites in the supernatant are then subjected to lyophilization (step 2) and reconstitution for subsequent mass spectrometric analyses (step 3).Back to article page