Table 1 A partial list of novel proteins upregulated in RA
| Â | Gene symbol | Protein | Molecular function | Cellular component | Fold change (RA/OA) |
|---|---|---|---|---|---|
1 | ARPC1B | Actin related protein 2/3 complex, subunit 1B, 41Â kDa | Cytoskeletal protein binding | Plasma membrane | 6.9 |
2 | CORO1A | Coronin, actin binding protein, 1A | Cytoskeletal protein binding | Cytoplasm | 6.0 |
3 | YWHAE | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide | Receptor signaling complex scaffold activity | Cytoplasm | 5.2 |
4 | CTSZ | Cathepsin Z | Cysteine-type protease activity | Lysosome | 3.9 |
5 | CAPG | Capping protein (actin filament), gelsolin-like | Cytoskeletal protein binding | Cytoplasm | 3.8 |
6 | FGL2 | Fibrinogen-like 2 | Extracellular matrix structural constituent | Extracellular | 3.5 |
7 | TYMP | Thymidine phosphorylase | Growth factor activity | Extracellular | 3.4 |