Table 1 Protein hits that are differentially expressed in SUR2KO-IR and WT-IR hearts

Mitochondrial peptide methionine sulfoxide reductase

Msra

0.0624981

0.19

1,4-alpha-glucan-branching enzyme

Gbe1

0.0221348

0.3

40S ribosomal protein S3

Rps3

0.0570084

0.32

Estradiol 17-beta-dehydrogenase 10

Hsd17b10

0.007576

0.48

Estradiol 17-beta-dehydrogenase 8

Hsd17b8

0.0257942

0.52

Dynamin-like 120 kDa protein

Opa1

0.0133927

0.59

Mitochondrial 2-oxoglutarate/malate carrier protein

Slc25a11

0.0229143

0.63

ATP synthase subunit gamma, mitochondrial

Atp5c1

0.0742584

0.66

ATP synthase subunit alpha, mitochondrial

Atp5a1

0.0866386

0.77

Cytochrome c oxidase subunit 5A, mitochondrial

Cox5a

0.0371111

0.79

Prohibitin-2

Phb2

0.0500592

1.3

Propionyl-CoA carboxylase beta chain, mitochondrial

Pccb

0.0813775

1.3

Heat shock protein HSP 90-beta

HSP90AB1

0.0215257

1.3

Cytochrome b-c1 complex subunit 1, mitochondrial

Uqcrc1

0.0602446

1.5

CDGSH iron-sulfur domain-containing protein 1

Cisd1

0.0446392

1.6

T-complex protein 1 subunit beta

Cct2

0.0880331

1.6

Basement membrane-specific heparan sulfate proteo-glycan core protein

Hspg2

0.0499444

1.6

Pyruvate dehydrogenase protein X component, mitochondrial

Pdhx

0.0121642

1.7

Catenin alpha-1

Ctnna1

0.0364573

1.7

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13

Ndufa13

0.0596356

1.7

Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial

Sdhb

0.0079267

1.7

Electron transfer flavoprotein subunit beta

Etfb

0.0489129

1.8

ATP synthase subunit d, mitochondrial

Atp5h

0.0923448

1.8

Hemoglobin subunit beta-1

Hbb-b1

0.032562

1.8

Cytochrome b-c1 complex subunit 8

Uqcrq

0.0703449

1.9

Ferritin light chain 1

Ftl1

0.0305524

1.9

Cofilin-1

Cfl1

0.0619513

1.9

Acyl-CoA dehydrogenase family member 10

Acad10

0.0765324

2

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7

Ndufa7

0.089645

2

Adenosylhomocysteinase

Ahcy

0.0612594

2.1

Lipoprotein lipase

LPL

0.0690628

2.3

Talin-1

Tln1

0.0040294

2.3

Laminin subunit gamma-1

Lamc1

0.0178447

2.4

Junction plakoglobin

Jup

0.0020557

2.6

AFG3-like protein 2

Afg3l2

0.0210335

2.9

Glutathione S-transferase P 1

Gstp1

0.0086305

3

NSFL1 cofactor p47

Nsfl1c

0.0965357

3.3

Ubiquitin carboxyl-terminal hydrolase 14

Usp14

0.0142878

4.4

Vesicle-associated membrane protein-associated protein B

Vapb

0.0669842

4.9

Adenylyl cyclase-associated protein 1

Cap1

0.034702

5.6

Glutaredoxin-1

Glrx

0.0590062

Only detected in KO