A feasibility study to identify proteins in the residual Pap test fluid of women with normal cytology by mass spectrometry-based proteomics

Table 1 Proteins identified in individual residual Pap test samples

	Individual Pap test samples
	NP94	NP134	NP137	NP929	NP933
Total number of proteins identified by MS/MS in this individual’s Pap test ^(a)	321	317	539	500	479
Number of this individual’s proteins also identified in the pooled samples ^(b)	280	257	293	311	286
Number of this individual’s proteins also identified in the “Normal Pap test Core Proteome” ^(c)	131	124	137	152	152

Proteins were identified from the MS/MS data for each of the 5 individual Pap test samples from women with normal cytology.
^(a)The total number of proteins identified in each individual Pap test was counted and the proteins listed in Additional file 2. False positive rates were < 1.0% for all experiments.
^(b)The lists of proteins that were identified for each individual were compared to the list of 714 proteins identified in the pooled Pap test samples (listed in Additional file 1).
^(c)The lists of proteins that were identified for each individual were compared to the list of 153 proteins identified in our newly defined “Normal Pap test Core Proteome” (listed in Table 2).

ISSN: 1559-0275