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Table 1 Demographics of training and validation study cohorts

From: Validation of a blood protein signature for non-small cell lung cancer

Characteristic

Training (n = 363)

UHH validation (n = 138)

EDRN validation (n = 135)

 

Case

Control

Case

Control

Case

Control

No. subjects

94

269

111

27

63

72

Median age (years)

69

57

62

58

68

71

Interquartile range

63-74

52-64

54-70

51-71

62-74

66-76

Gender

      

Male

42

126

70

13

36

39

Female

52

143

41

14

27

33

Median pack-years*

40

40

35

30

60

38

Interquartile range

23-57

20-56

20-50

18-43

40-76

34-60

Histopathology/Stage

      

Adenocarcinoma

64

 

55

 

38

 

I

27

 

19

 

24

 

II

7

 

16

 

5

 

III

19

 

20

 

7

 

IV

11

 

0

 

2

 

Squamous cell

30

 

56

 

25

 

I

11

 

20

 

14

 

II

5

 

16

 

4

 

III

12

 

20

 

3

 

IV

2

 

0

 

4

 

Benign nodule

 

122

 

27

 

20

  1. *Pack-years is defined as the product of the total number of years of smoking and the average number of packs of cigarettes smoked daily.
  2. Smoking data was not available for 8 subjects in training, 21 in UHH and 10 in EDRN studies.