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Table 1 Proteins differentially expressed in both AVS ventricles compared to at least one CAD ventricle

From: The effect of disease on human cardiac protein expression profiles in paired samples from right and left ventricles

  Log2fold diff. vs. RVCAD
Protein [Swiss-Prot accession number] LVCAD RVAVS LVAVS
Both ventricles of AVS vs. both ventricles of CAD
Glycogen [starch] synthase, muscle [P13807] 0.25* 0.85*# 0.72*#
2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial [P12694] 0.08 0.54*# 0.52*#
Sodium channel protein type 5 subunit alpha [Q14524] −0.10 0.43*# 0.65*#
Apoptotic chromatin condensation inducer in the nucleus [Q9UKV3] 0.09 −0.50*# −0.51*#
Both ventricles of AVS vs. one ventricle of CAD
Unconventional myosin-XVIIIb [Q8IUG5] 0.09 0.81*# 0.79*
Nestin [P48681] 0.23 0.60* 0.53*
Thiomorpholine-carboxylate dehydrogenase [Q14894] 0.19 0.52* 0.74*
60 kDa heat shock protein, mitochondrial [P10809] 0.25* 0.48* 0.39*
PDZ and LIM domain protein 5 [Q96HC4] 0.05 0.45* 0.30*
Amine oxidase [flavin-containing] A [P21397] 0.28 0.45* 0.34*
Peptidyl-prolyl cis-trans isomerase F, mitochondrial [P30405] 0.15 0.44* 0.39*
ATP-binding cassette sub-family F member 1 [Q8NE71] 0.06 0.43*# 0.27*
Enoyl-CoA delta isomerase 2, mitochondrial [O75521] 0.18 0.39* 0.32*
Hexokinase-1 [P19367] 0.26 0.39* 0.43*
Protein NipSnap homolog 2 [O75323] 0.08 0.33* 0.29*
Phosphoglycerate mutase 1 [P18669] 0.16* 0.33* 0.33*
GTP:AMP phosphotransferase AK4, mitochondrial [P27144] 0.18 0.32* 0.23*
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial [Q16836] 0.17* 0.31* 0.23*
Aspartate aminotransferase, mitochondrial [P00505] 0.13 0.30* 0.24*
Annexin A11 [P50995] 0.10* 0.30* 0.22*
Glutathione S-transferase kappa 1 [Q9Y2Q3] 0.09 0.28* 0.26*
Elongation factor Tu, mitochondrial [P49411] 0.13* 0.26* 0.22*
Moesin [P26038] 0.03 0.23*# 0.21*
Alpha-2-macroglobulin [P01023] 0.37 −0.77* −0.71*
Alpha-1-acid glycoprotein 1 [P02763] 0.09 −0.80* −0.69*
Haptoglobin [P00738] 0.28 −1.46* −1.41*
Elongation factor 1-alpha 2 [Q05639] −0.07 0.16*# 0.09#
Peroxiredoxin-1 [Q06830] −0.04 −0.17# −0.23#
Proactivator polypeptide [P07602] 0.24* −0.33# −0.34#
Heterogeneous nuclear ribonucleoproteins C1/C2 [P07910] 0.05 −0.60# −0.61#
  1. Proteins significantly altered in both the left and right ventricles of the AVS patients compared to the left and/or right ventricle(s) of CAD patients. Data are presented as log2 fold difference compared to the right ventricle of the CAD patients.
  2. *P < 0.05 vs. RVCAD and #P < 0.05 vs. LVCAD.
  3. Fold diff. = Fold difference.