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Table 1 Proteins differentially expressed in both AVS ventricles compared to at least one CAD ventricle

From: The effect of disease on human cardiac protein expression profiles in paired samples from right and left ventricles

 

Log2fold diff. vs. RVCAD

Protein [Swiss-Prot accession number]

LVCAD

RVAVS

LVAVS

Both ventricles of AVS vs. both ventricles of CAD

Glycogen [starch] synthase, muscle [P13807]

0.25*

0.85*#

0.72*#

2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial [P12694]

0.08

0.54*#

0.52*#

Sodium channel protein type 5 subunit alpha [Q14524]

−0.10

0.43*#

0.65*#

Apoptotic chromatin condensation inducer in the nucleus [Q9UKV3]

0.09

−0.50*#

−0.51*#

Both ventricles of AVS vs. one ventricle of CAD

Unconventional myosin-XVIIIb [Q8IUG5]

0.09

0.81*#

0.79*

Nestin [P48681]

0.23

0.60*

0.53*

Thiomorpholine-carboxylate dehydrogenase [Q14894]

0.19

0.52*

0.74*

60 kDa heat shock protein, mitochondrial [P10809]

0.25*

0.48*

0.39*

PDZ and LIM domain protein 5 [Q96HC4]

0.05

0.45*

0.30*

Amine oxidase [flavin-containing] A [P21397]

0.28

0.45*

0.34*

Peptidyl-prolyl cis-trans isomerase F, mitochondrial [P30405]

0.15

0.44*

0.39*

ATP-binding cassette sub-family F member 1 [Q8NE71]

0.06

0.43*#

0.27*

Enoyl-CoA delta isomerase 2, mitochondrial [O75521]

0.18

0.39*

0.32*

Hexokinase-1 [P19367]

0.26

0.39*

0.43*

Protein NipSnap homolog 2 [O75323]

0.08

0.33*

0.29*

Phosphoglycerate mutase 1 [P18669]

0.16*

0.33*

0.33*

GTP:AMP phosphotransferase AK4, mitochondrial [P27144]

0.18

0.32*

0.23*

Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial [Q16836]

0.17*

0.31*

0.23*

Aspartate aminotransferase, mitochondrial [P00505]

0.13

0.30*

0.24*

Annexin A11 [P50995]

0.10*

0.30*

0.22*

Glutathione S-transferase kappa 1 [Q9Y2Q3]

0.09

0.28*

0.26*

Elongation factor Tu, mitochondrial [P49411]

0.13*

0.26*

0.22*

Moesin [P26038]

0.03

0.23*#

0.21*

Alpha-2-macroglobulin [P01023]

0.37

−0.77*

−0.71*

Alpha-1-acid glycoprotein 1 [P02763]

0.09

−0.80*

−0.69*

Haptoglobin [P00738]

0.28

−1.46*

−1.41*

Elongation factor 1-alpha 2 [Q05639]

−0.07

0.16*#

0.09#

Peroxiredoxin-1 [Q06830]

−0.04

−0.17#

−0.23#

Proactivator polypeptide [P07602]

0.24*

−0.33#

−0.34#

Heterogeneous nuclear ribonucleoproteins C1/C2 [P07910]

0.05

−0.60#

−0.61#

  1. Proteins significantly altered in both the left and right ventricles of the AVS patients compared to the left and/or right ventricle(s) of CAD patients. Data are presented as log2 fold difference compared to the right ventricle of the CAD patients.
  2. *P < 0.05 vs. RVCAD and #P < 0.05 vs. LVCAD.
  3. Fold diff. = Fold difference.
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Clinical Proteomics

ISSN: 1559-0275