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Table 2 Inter-disease trends: metabolism-related proteins

From: The effect of disease on human cardiac protein expression profiles in paired samples from right and left ventricles

  Log2fold diff. vs. RVCAD
Protein [Swiss-Prot accession number] LVCAD RVAVS LVAVS
Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial [P55809] 0.14 0.63*# 0.37
UTP--glucose-1-phosphate uridylyltransferase [Q16851] 0.03 0.47*# 0.37
ADP/ATP translocase 2 [P05141] 0.11 0.42*# 0.38
Acyl-coenzyme A thioesterase 9, mitochondrial [Q9Y305] −0.05 0.39*# 0.29
Dihydrolipoyl dehydrogenase, mitochondrial [P09622] 0.12 0.37*# 0.28
Cytochrome c [P99999] 0.05 0.31*# 0.24
Phosphoglucomutase-1 [P36871] −0.02 0.15*# 0.07
Acetyl-coenzyme A synthetase, cytoplasmic [Q9NR19] 0.07 −0.20*# −0.17
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial [P11310] 0.09 0.42* 0.34
D-beta-hydroxybutyrate dehydrogenase, mitochondrial [Q02338] 0.20 0.41* 0.34
Enoyl-CoA hydratase, mitochondrial [P30084] 0.15* 0.38* 0.26
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial [P10515] 0.12 0.35* 0.29
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial [P36957] 0.10 0.34* 0.26
Fumarate hydratase, mitochondrial [P07954] 0.12 0.34* 0.25
Amine oxidase [flavin-containing] B [P27338] 0.06 0.25* 0.13
ADP/ATP translocase 1 [P12235] 0.13 0.24* 0.15
Electron transfer flavoprotein subunit beta [P38117] 0.08* 0.22* 0.14
Fatty acid-binding protein, heart [P05413] 0.03 0.21* 0.18
Malate dehydrogenase, cytoplasmic [P40925] 0.05 0.20* 0.13
Pyruvate dehydrogenase protein X component, mitochondrial [O00330] 0.05 0.34# 0.27
Glycogen phosphorylase, brain form [P11216] −0.01 0.29# 0.23
Phosphatidate cytidylyltransferase 2 [O95674] 0.01 0.26# 0.17
Triosephosphate isomerase [P60174] 0.05 −0.04# −0.03
  1. Proteins (metabolism-related) significantly altered in one of the AVS ventricles compared to either the left or right ventricle of CAD group and had a similar trend in the adjacent AVS ventricle. Data are presented as log2 fold difference compared to the right ventricle of the CAD patients.
  2. *P < 0.05 vs. RVCAD and #P < 0.05 vs. LVCAD.
  3. Fold diff. = Fold difference.