The effect of disease on human cardiac protein expression profiles in paired samples from right and left ventricles

Table 4 Inter-disease trends: other proteins

	Log₂fold diff. vs. RV_CAD
Protein [Swiss-Prot accession number]	LV_CAD	RV_AVS	LV_AVS
Adenylyl cyclase-associated protein 2 [P40123]	0.01	0.49*^#	0.50
Sarcolemmal membrane-associated protein [Q14BN4]	0.11	0.48*^#	0.37
Dynamin-like 120 kDa protein, mitochondrial [O60313]	0.15	0.43*^#	0.31
Calnexin [P27824]	0.10	0.39*^#	0.20
Popeye domain-containing protein 2 [Q9HBU9]	0.03	0.38*^#	0.22
CDGSH iron-sulfur domain-containing protein 1 [Q9NZ45]	0.11	0.36*^#	0.28
Ubiquitin-conjugating enzyme E2 L3 [P68036]	−0.04	0.16*^#	0.28
Protein Smaug homolog 1 [Q9UPU9]	0.18	0.63*	0.51
Myelin basic protein [P02686]	0.29	0.61*	0.61
Ras-related protein R-Ras2 [P62070]	0.25	0.61*	0.66
BRISC and BRCA1-A complex member 1 [Q9NWV8]	0.23*	0.45*	0.55
28S ribosomal protein S36, mitochondrial [P82909]	0.17	0.34*	0.31
Protein QIL1 [Q5XKP0]	0.14	0.34*	0.26
LIM domain-binding protein 3 [O75112]	0.19	0.33*	0.23
ES1 protein homolog, mitochondrial [P30042]	0.16*	0.29*	0.27
Transitional endoplasmic reticulum ATPase [P55072]	0.06	0.22*	0.12
Anion exchange protein 3 [P48751]	−0.09	−0.40*	−0.26
Complement C3 [P01024]	0.08	−0.80*	−0.67
Cysteine and glycine-rich protein 3 [P50461]	0.01	0.57^#	0.37
Eukaryotic translation initiation factor 5B [O60841]	−0.10	0.30^#	0.26
Calpastatin [P20810]	0.34	0.76	0.69*
Protein PBDC1 [Q9BVG4]	0.13	0.26	0.34*
Proline-rich basic protein 1 [E7EW31]	−0.02	−0.26	−0.41*

Other proteins significantly altered in one of the AVS ventricles compared to either the left or right ventricle of CAD group and had a similar trend in the adjacent AVS ventricle. Data are presented as log₂ fold difference compared to the right ventricle of the CAD patients.
*P < 0.05 vs. RV_CAD and ^#P < 0.05 vs. LV_CAD.
Fold diff. = Fold difference.

ISSN: 1559-0275