Proteomic signatures of serum albumin-bound proteins from stroke patients with and without endovascular closure of PFO are significantly different and suggest a novel mechanism for cholesterol efflux

Table 3 Abundance ratios and ROC AUC of albumin-bound proteins common to both PFO Closure and No Closure stroke samples

GI	Protein	ROC AUC baseline Closure/Follow up	ROC AUC baseline No Closure/Follow up	Ratio baseline Closure/Follow up	Ratio baseline No Closure/Follow up
4557321	apolipoprotein A-I preproprotein [Homo sapiens]	0.950	0.76	1.46	1.26
4557323	apolipoprotein C-III precursor [Homo sapiens]	0.89	0.76	2.00	1.17
19923106	serum paraoxonase/arylesterase 1 precursor [Homo sapiens]	0.87	0.80	1.69	1.26
4502157	apolipoprotein C-I precursor [Homo sapiens]	0.87	0.52*	0.92	0.9
32483410	vitamin D-binding protein isoform 1 precursor [Homo sapiens]	0.87	0.80	2.16	1.53
32130518	apolipoprotein C-II precursor [Homo sapiens]	0.84	0.80	0.92	1.35
4504893	kininogen-1 isoform 2 precursor [Homo sapiens]	0.655*	0.92	0.85	1.35
4502149	apolipoprotein A-II preproprotein [Homo sapiens]	0.628*	0.684*	0.92	1.08

ISSN: 1559-0275