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Table 3 Coefficient of variation (CV) of protein abundance as evaluated on the 10 HPS samples in Study I

From: An integrated quantification method to increase the precision, robustness, and resolution of protein measurement in human plasma samples

Protein (HUMAN) CV (%) CV reduction (%)
InteQuan SISQuan EPN Raw SISQuan-InteQuan EPN-SISQuan Raw-EPN
KIT 8.8 9.6 15.0 24.1 0.8 5.4 9.2
FRIL 16.8 25.2 21.9 28.0 8.4 -3.3 6.1
COIA1 12.6 17.8 20.3 27.2 5.2 2.5 7.0
PRDX1 10.7 15.4 12.1 19.7 4.7 -3.3 7.6
TENX 11.1 13.6 9.6 20.2 2.5 -4.0 10.6
ENPL 13.1 18.9 6.9 19.1 5.8 -12.0 12.2
GRP78 6.8 11.4 16.7 22.5 4.5 5.3 5.8
BGH3 5.0 12.3 16.7 23.3 7.3 4.4 6.5
ALDOA 6.6 13.6 17.7 28.6 7.0 4.1 11.0
GGH 6.9 7.1 6.8 17.2 0.2 -0.3 10.3
CD14 4.1 8.0 21.1 31.8 3.8 13.1 10.7
LG3BP 8.8 13.0 8.8 19.4 4.2 -4.2 10.6
TSP1 11.6 18.3 19.6 22.5 6.7 1.3 2.8
IBP3 5.7 11.6 5.7 12.4 5.9 -5.9 6.6
TETN 9.9 17.8 19.6 21.7 7.9 1.8 2.1
ISLR 10.0 9.1 13.5 20.5 -0.9 4.4 7.0
Median 9.3 13.3 15.9 22.1 4.9 1.6 7.3
P value (paired sign test)    5.2 × 10 -04 0.80 3.1 × 10 -05