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Table 1 Proteins higher in abundance in tumour relative to matched normal mucosa

From: Desmin expression in colorectal cancer stroma correlates with advanced stage disease and marks angiogenic microvessels

   2D DIGE DeCyder™ calculations Mass spectrometry
Spot number Protein identified Patient T-N spot volume ratio Ave. Ratio P value Score Peptides Matched % seq. MS/MS
1 Desmin 1 2.79 2.25 0.02 500 b 11 31
  P17661a 2 1.19      
   3 1.58      
   4 3.45      
2 HSP60 1 3.51 2.57 0.01 12.4c 7 10
  P10809 2 1.46      
   3 1.91      
   4 3.10      
3 14-3-3 β 1 1.48 2.0 0.01 234 b 6 28
  P31946 2 1.57      
   3 1.65      
   4 3.46      
4 β Tubulin 1 1.59 2.98 0.017 117b 2 5
  P07437 2 3.01      
   3 3.55      
   4 2.42      
  1. a, UniProtKB database accession number; b, Probability-based Mowse score (Mascot search engine at Matrixscience.com); c, Protein Lynx score (Protein Lynx Global server) - an algorithm based measure of confidence of protein identity; d, Percentage sequence coverage for MS/MS identification.