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Table 2 List of differentially expressed serum proteins in visceral leishmaniasis identified by Q-TOF-MS/MSf

From: Two-dimensional difference gel electrophoresis (DIGE) analysis of sera from visceral leishmaniasis patients

Spot noa.

Protein name

Accession no.b

Average ratiodratio ('p' (p value)

Appaerance in gels (n = 18)

Mascot Scoree

Peptide matches

Coverage (%)

129

C1 inhibitor

gi|73858570

+1.45 (0.026)

18

190

22

32

1051

Alpha-1- acid glycoprotein

gi|112877

+3.73 (0.009)

18

166

13

48

954

Transthyretin

gi|126030594

-1.83 (0.001)

18

449

13

95

958

Transthyretin

gi|126030594

-2.23 (0.011)

18

503

12

84

1050

Transthyretin

gi|219978

-1.84 (0.015)

18

188

5

46

1049

Transthyretin

gi|443295

-2.22 (0.011)

18

262

5

38

816

Retinol binding protein

gi|4558179

-1.99 (0.009)

18

47

6

27

673

Apolipoprotein A-I

gi|113992

-2.24 (0.013)

18

114

8

27

746

Apolipoprotein A-I

LPHUA1c

-1.65 (0.015)

18

314

28

63

  1. a Spot no. assigned in DeCyder analysis and corresponded to the DIGE image in Figure 1
  2. bAccession no. from NCBInr database, c MSDB database
  3. d+ indicates up-regulation and - indicates down-regulation of the protein in visceral leishmaniasis serum with reference to controls.
  4. e Mascot scores greater than 40 were considered significant
  5. f Details of all the mascot search results are provided as additional files 2 and 3.