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Figure 3 | Clinical Proteomics

Figure 3

From: Virtual screening and evaluation of Ketol-Acid Reducto-Isomerase (KARI) as a putative drug target for Aspergillosis

Figure 3

Ribbon representation of KARI model (A) with the ligand in green color (B). Important residues are shown (Ser, Arg and Val.) and the distance was calculated from the active site that is serine residue (ser-184) to N-terminal (31.97Å) and C- (30.57 Å) terminals of the model receptor as calculated by pymol are shown. The inset shows the length (12.49 Å) of (4R)-6-amino-3-(3,4-dimethoxyphenyl)-4-(5-(4-fluorophenyl)-1H-pyrazol-4-yl)-2,4 dihydropyrano(2,3-c)pyrazole-5-carbonitrile.

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