Figure 1From: Quantitative proteomics for identifying biomarkers for tuberculous meningitisOutline of the quantitative proteomic strategy. TBM-infected and uninfected frontal cortex tissues were used to extract proteins and subjected to digestion with trypsin. Peptides from the two groups were labeled with iTRAQ reagents followed by LC-MS/MS on a QTOF mass spectrometer. A subset of the differentially expressed molecules were validated by immunohistochemistry.Back to article page