Figure 3
From: Urine proteome of autosomal dominant polycystic kidney disease patients
Principal Component Analysis of the three pooled biological replicates of control (CPS I, II, and III) and disease (DPS I, II and III) samples based on 155 proteins (grey dots) indicated in the analysis as differentially populated between control and ADPKD samples. The analysis shows a good separation of control samples from ADPKD samples along the first component axis. Note a high similarity of control samples. Normalized heights of iTRAQ peptide signals (averaged over the corresponding protein cluster) were used as features in the PCA analysis. Values of each biological replicate is an average over the two technical replicates.