Table 4 Confirmation and validation with an independent method (ELISA) of MS peaks with the highest ROC AUC combination (0.91)
From: Ovarian cyst fluid is a rich proteome resource for detection of new tumor biomarkers
Protein | Confirmation set | Validation set | ||||
|---|---|---|---|---|---|---|
Benign | Malignant | Sign. | Benign | Malignant | Sign. | |
Median | Median | Median | Median | |||
(range) | (range) | (range) | (range) | |||
APOC3 | 5.16 | 13.1 | p < 0.05 | 3.3 | 22.7 | p = 0.001 |
(0.2-52.8) | (0.6-51.7) | (0.04-35.2) | (1.8-377.0) | |||
PCI | 52.8 | 100.4 | NS | 4.7 | 14.9 | NS |
(17.5-177.7) | (20.0-691.8) | (0.0-332.9) | (0.0-196.2) | |||