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Table 1 List of candidate biomarker proteins found at higher abundance in prostatitis compared to control, according to spectral counting.

From: Characterization of the seminal plasma proteome in men with prostatitis by mass spectrometry

Gene Name

Average Spectral Count

Fold Change*

Prostatic Origin**

 

Control

Prostatitis

  

ALB

1441

3079

2.1

 

SERPINA1

149

382

2.6

Yes

CST4

83

468

5.7

 

CST3

65

202

3.1

Yes

PAEP cDNA FLJ52183

52

144

2.8

 

C4A

38

131

3.5

Yes

A2M

44

103

2.3

Yes

SERPINA5

37

122

3.3

 

C3

34

104

3

Yes

LPL

30

66

2.2

 

IGHG2

17

46

2.6

 

A1BG

25

50

2

 

MSLN

16

33

2

 

SERPING1

17

48

2.9

 

SCPEP1

17

44

2.6

Yes

GLA

21

43

2

Yes

OLFM4

15

41

2.7

Yes

SMPD1

9

20

2.2

Yes

CTSF

9

24

2.5

Yes

SERPINF1

10

33

3.4

Yes

MINPP1

9

19

2.1

Yes

CFI

9

18

2.1

 

CTSC

5

10

2.2

 

CST6

7

15

2.2

Yes

TXNDC16

8

18

2.3

Yes

LCN1

2

15

6.3

 

COL6A2

3

15

5.5

Yes

A4GALT

4

15

4

Yes

PATE4

4

13

3

Yes

TIMP3

5

11

2.1

 

CST2

2

16

9.6

 

FGB

4

11

2.6

 

COMP

4

12

2.9

 
  1. * Fold change = average prostatitis/average control
  2. ** Protein/gene name annotated as expressed in the prostate in at least 2 out of 3 databases (BioGPS; Unigene, Protein Atlas)