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Table 2 List of candidate biomarker proteins found at higher abundance in control compared to prostatitis, according to spectral counting.

From: Characterization of the seminal plasma proteome in men with prostatitis by mass spectrometry

Gene Name

Average Spectral Count

Fold Change*

Prostatic Origin**

 

Control

Prostatitis

  

CPM

31

10

3

Yes

DYNC1H1

29

13

2.3

 

MUC5B

29

7

4.2

 

RAB27B

21

11

2

Yes

PHGDH

20

10

2.1

Yes

CA2

19

9

2

 

ACO1

14

6

2.3

Yes

ANXA6

19

5

3.5

 

CACNA2D1

19

5

4

 

FAM129A

10

4

2.4

Yes

CDC42

12

4

2.7

Yes

RHOC

13

4

3.2

Yes

HGD

14

5

2.9

 

RAB2A

11

5

2.1

Yes

DCXR

12

6

2.1

Yes

LAMP1

10

4

2.3

Yes

ALDH9A1

11

5

2

Yes

CMPK1

13

5

2.5

 

NOV

13

5

2.4

Yes

NAPA

12

4

2.8

Yes

SOD3

12

5

2.3

Yes

LIFR

11

5

2.3

Yes

RNPEP

12

5

2.2

Yes

FLNB

13

4

3.2

Yes

DDAH1

12

5

2.3

Yes

KIF5B

11

4

3.1

Yes

  1. * Fold change = average control/average prostatitis
  2. ** Protein/gene name annotated as expressed in the prostate in at least 2 out of 3 databases (BioGPS; Unigene, Protein Atlas)