Figure 1
From: The cerebrospinal fluid proteome in HIV infection: change associated with disease severity
CSF HIV RNA and neopterin in HIV-infected subjects. The panels show the longitudinal changes (A - K) and the three singly sampled results for CSF HIV RNA and CSF neopterin from the 14 HIV-infected subjects. In the longitudinal panels all subjects initiated cART at time 0 (subjects in panels I-K were observed before starting therapy which is marked by vertical arrow and 0 time scale). The blood CD4+ T cell counts, QNZP-4 performance score, ADC stage and CSF NFL at this baseline are shown in each panel. In the aggregate these sample a broad range of subjects in different stages of untreated and treated HIV infection and CNS disease. Symbols defined in panel A apply to all the panels.