Table 1 Subject and CSF background characteristics
From: The cerebrospinal fluid proteome in HIV infection: change associated with disease severity
| Â | HIV Infected Baseline | HIV Infected All Samples Median (IQR)* | HIV Negative |
|---|---|---|---|
Number | 14 | 79 | 12 |
Age (mean years, SD) | 46.6 (7.6) | 48.0 (7.9) | 45.7 (5.1) |
Gender (M/F) | 12/2 | 59/20 | 10/2 |
Blood T cells (mean cells/μL, SD) | |||
   CD4+ | 217.1 (155.9) | 268.2 (166.7) | 902.4 (265.4) |
   CD8+ | 896.1 (573.0) | 933.7 (662.7) | 481.9 (243.6) |
HIV-1 RNA (log10 copies/mL) | |||
   plasma | 4.29 (3.74 - 5.15) | 3.40 (1.72 - 4.76) | NA |
   CSF | 4.92 (4.26 - 5.36) | 3.85 (1.71 - 4.47) | NA |
CSF WBCs (per μL) | 15 (6.3 - 20.3) | 11 (5.0 - 22.0) | 1.0 (0.3 - 2.0) |
CSF Neopterin (nMol/L) | 34.8 (22.2 - 48.7) | 23.6 (14.0 - 44.3) | 4.6 (3.3 - 6.2) |
CSF NFL (ng/L) | 124 (124 - 1846) | 235.2 (124.0 - 2460.0) | 124 (124 - 124) |
QNPZ-4 | -1.30 (-3.43 - 0.28) | -1.70 (-3.35 - 0.45) | 0.00 (-0.85 - 0.46) |
CSF:blood albumin ratio (mean, SD) | 7.946 (3.508) | 7.818 (4.074) | 5.355 (2.055) |