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Table 1 EGFR-SRM analysis of formalin-fixed paraffin-embedded (FFPE) human xenograft tissue of non-small cell lung carcinoma (NSCLC) origin

From: Selected Reaction Monitoring (SRM) Analysis of Epidermal Growth Factor Receptor (EGFR) in Formalin Fixed Tumor Tissue

Sample

Histology Subtype

Cellular Differentiation

EGFRSRM (amo/μg total protein)

CV%

ADC1

Adeno

Moderate

2,113

9.6

ADC2

Adeno

Poor

3,378

4.6

ADC3

Adeno

Moderate

5,591

9.6

ADC4

Adeno

Poor

305

10.9

ADC5

Adeno

Poor

312

9.2

SCC1

Squamous

Well

467

0.2

SCC2

Squamous

Well

826

0.2

SCC3

Squamous

Moderate

12,860

0.3

SCC4

Squamous

Poor

757

40

SCC5

Squamous

Moderate

1,736

1.4

  1. Results are standardized to total amount of protein. SRM analysis is consistent with previously published western blot, immunohistochemistry (IHC), and SRM analysis of the matched frozen xenograft tissue [21].