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Table 3 Patient characteristics as stratified by Nm23/NDPK-A status

From: Nm23/nucleoside diphosphate kinase-A as a potent prognostic marker in invasive pancreatic ductal carcinoma identified by proteomic analysis of laser micro-dissected formalin-fixed paraffin-embedded tissue

Variable

Category

All patients (n = 96)

Nm23/NDPK-A positive (n = 73)

Nm23/NDPK-A negative (n = 23)

P value

Age

< 65

45 (47%)

32 (44%)

13 (57%)

0.2877

 

≥ 65

51 (53%)

41 (56%)

10 (43%)

 

Gender

Male

62 (65%)

45 (62%)

17 (74%)

0.2833

 

Female

34 (35%)

28 (38%)

6 (26%)

 

Location

Head

73 (76%)

56 (77%)

17 (74%)

0.7839

 

Body-Tail

23 (24%)

17 (23%)

6 (26%)

 

Histological differentiationa

Well

8 (8%)

6 (8%)

2 (9%)

0.9838

 

Moderate + Poor

77 (80%)

58 (80%)

19 (82%)

 

Tumor stage

T1 + T2

10 (10%)

7 (10%)

3 (13%)

0.6363

 

T3 + T4

86 (90%)

66 (90%)

20 (87%)

 

Nodal stage

N0

33 (34%)

25 (34%)

8 (35%)

0.9624

 

N1

63 (66%)

48 (66%)

15 (65%)

 

NCCNb criteria

Resectable

50 (52%)

38 (52%)

12 (52%)

0.9920

 

Borderline rsectable

46 (48%)

35 (48%)

11 (48%)

 

Preoperative CA19-9

< 37 U/mL

25 (26%)

17 (23%)

8 (35%)

0.2733

 

≥ 37 U/mL

71 (74%)

56 (77%)

15 (65%)

 

Postoperative CA19-9

< 37 U/mL

57 (59%)

41 (56%)

16 (70%)

0.2538

 

≥ 37 U/mL

39 (41%)

32 (44%)

7 (30%)

 

Adjuvant chemotherapy

Gemcitabine

58 (60%)

42 (58%)

16 (70%)

0.3035

 

Othersc

38 (40%)

31 (42%)

7 (30%)

 
  1. a Other histological classifications including papillary, mucinous, adenosquamous and anaplastic carcinoma in 11 cases.
  2. b National Comprehensive Cancer Network.
  3. c Others include 5FU and surgery alone.