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Table 3 Protein biomarkers with significant difference ( p <0.01) between lamotrigine treated and untreated SPMS group

From: Development of protein biomarkers in cerebrospinal fluid for secondary progressive multiple sclerosis using selected reaction monitoring mass spectrometry (SRM-MS)

Protein

p-value(1)

Ratio(2)

1433F

0.0005

3.37

1433G

0.0017

2.71

AACT

0.0037

2.55

CAD13

0.0018

2.75

TAU

0.0003

2.84

NFH

0.0007

2.25

NFL

0.0011

2.60

NFM

0.0004

4.47

NRCAM

0.0005

2.85

OSTP

0.0062

5.10

SAMP

0.0004

2.64

  1. (1) p-value of ANOVA (7 treated vs. 22 untreated SPMS subjects).
  2. (2) The ratios of untreated to treated group median.
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Clinical Proteomics

ISSN: 1559-0275