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Table 1 Comparison of identification scores for specimens extracted using the EFAE and newly developed NECLC approach

From: Identification of Nocardia species using matrix-assisted laser desorption/ionization–time-of-flight mass spectrometry

 

EFAE

NECLC

P value

Nocardia isolate

Mean ± SD

Mean ± SD

N. nova-2010/742

1.94 ± 0.06

2.11 ± 0.03

0.00008909***

N. nova-2011/258

1.89 ± 0.04

2.12 ± 0.04

0.00000340***

N. otitidiscaviarum-2010/435

1.94 ± 0.09

2.10 ± 0.06

0.00557253**

N. otitidiscaviarum-2012/744

1.68 ± 0.10

2.01 ± 0.10

0.00001193***

N. farcinica-2011/1341

1.27 ± 0.13

1.39 ± 0.08

0.02787181*

N. farcinica-2012/241

1.24 ± 0.08

1.37 ± 0.10

0.02223143*

N. elegans-2011/259

-

1.28 ± 0.15

#

N. elegans-2010/1158

1.22 ± 0.05

1.46 ± 0.10

0.00000972***

N. cyriacigeorgica-2011/531

-

1.33 ± 0.09

#

N. cyriacigeorgica-2012/1454

1.25 ± 0.10

1.40 ± 0.01

0.00209917**

  1. Three colonies obtained from each of the various Nocardia isolates were analyzed. Each colony was subjected to 3 independent extraction/MS runs, and the identification scores obtained were compared statistically.
  2. *: indicates isolate showing significant improvement (P < 0.05). **: P < 0.01, ***: P < 0.0001, #: indicates sufficient mass spectra for scoring could not be obtained using the EFAE method.