Table 3 Amplitudes of most important urinary protein by clinical diagnosis
From: Urinary proteomics in chronic kidney disease: diagnosis and risk of progression beyond albuminuria
Peptide information | SwissProt name | Mean amplitude | Fold changes | ||||||
|---|---|---|---|---|---|---|---|---|---|
Peptide name | Control | HN | GN + DN | Others | Control | HN | GN + DN | Others | |
Alpha-1-antitrypsin | A1AT_HUMAN | 39 | 11,031 | 21,119 | 21,236 | 1 | 282.5 | 540.9 | 543.9 |
Serum albumin | ALBU_HUMAN | 0 | 23,348 | 78,627 | 13,663 | ||||
Apolipoprotein A-I | APOA1_HUMAN | 47 | 127,871 | 110,906 | 38,500 | 1 | 2,713.9 | 2,353.8 | 817.1 |
Na/K-transp. ATPase gamma chain | ATNG_HUMAN | 1,984 | 396 | 322 | 450 | 1 | 0.2 | 0.2 | 0.2 |
Beta-2-microglobulin | B2MG_HUMAN | 0 | 239,173 | 677,860 | 207,089 | ||||
CD99 antigen | CD99_HUMAN | 1,357 | 0 | 28 | 129 | 1 | 0.0 | 0.0 | 0.1 |
Collagen alpha-1 (I) chain | CO1A1_HUMAN | 3,078 | 1,533 | 1,123 | 2,455 | 1 | 0.5 | 0.4 | 0.8 |
Collagen alpha-1 (II) chain | CO2A1_HUMAN | 3,190 | 1,344 | 500 | 1,367 | 1 | 0.4 | 0.2 | 0.4 |
Collagen alpha-1 (III) chain | CO3A1_HUMAN | 2,338 | 1,064 | 717 | 1,246 | 1 | 0.5 | 0.3 | 0.5 |
Alpha-2-HS-glycoprotein | FETUA_HUMAN | 43 | 12,128 | 14,441 | 6,950 | 1 | 283.7 | 337.8 | 162.5 |
Fibrinogen alpha chain | FIBA_HUMAN | 965 | 14,993 | 2,308 | 6,477 | 1 | 15.5 | 2.4 | 6.7 |
Osteopontin | OSTP_HUMAN | 410 | 0 | 0 | 39 | 1 | 0.0 | 0.0 | 0.1 |
Membrane associated progesterone receptor component 1 | PGRC1_HUMAN | 536 | 1,017 | 8 | 502 | 1 | 1.9 | 0.0 | 0.9 |
Polymeric-immunoglobulin receptor | PIGR_HUMAN | 1,624 | 583 | 584 | 740 | 1 | 0.4 | 0.4 | 0.5 |
Transthyretin (Prealbumin) | TTHY_HUMAN | 15 | 22,299 | 53,034 | 22,292 | 1 | 1,471.6 | 3,499.9 | 1,471.2 |
Uromodulin | UROM_HUMAN | 2,525 | 89 | 136 | 176 | 1 | 0.0 | 0.1 | 0.1 |
Neurosecretory protein VGF | VGF_HUMAN | 1,770 | 9,796 | 6,140 | 5,644 | 1 | 5.5 | 3.5 | 3.2 |