Fig. 1
From: Proteomic profiling identifies specific histone species associated with leukemic and cancer cells
Histone H2A isoforms altered in CLL. a A representative spectrum histone H2A. The peaks that are significantly changed in CLL, bladder and breast cancer cells are highlighted with arrows (CLL-green, bladder-red and breast-blue). b Comparison of H2A 1C and H2A 1B/1E in normal B cells vs CLL patient B cells. c Representative spectrum showing the presence or absence of the peak with molecular weight 14,063 Da in healthy (top) CLL patient (bottom) B cells. d Kaplan–Meier curve showing the comparison of time to treatment in patients with and without the 14,063 Da peak