New biomarkers for primary mitral regurgitation

Table 1 Demographic, echocardiographic characteristics and risk factors of MR patients and healthy controls

Variables	HC (n = 16)	MR severity			p values
		Mild (n = 23)	Moderate (n = 21)	Severe (n = 20)	p values
		Mild (n = 23)	Moderate (n = 21)	Severe (n = 20)	A	B
Demographic data
Age, years	59.44 ± 7.54	62.04 ± 10.84	61.23 ± 11.99	60.81 ± 12.85	0.91	0.92
Male sex, n (%)	8 (50)	10 (43)	12 (57)	16 (80)	0.09	0.05
Height, m	1.70 ± 0.11	1.72 ± 0.11	1.68 ± 0.08	1.71 ± 0.09	0.80	0.58
Weight, kg	77.64 ± 19.31	74.45 ± 14.85	69.56 ± 11.69	78.3 ± 13.6	0.35	0.19
Body mass index, kg/m²	26.36 ± 3.98	24.65 ± 3.91	24.25 ± 2.88	26.33 ± 4.21	0.26	0.22
Waist circumference, cm	95.73 ± 16.67	96.22 ± 9.91	95.5 ± 11.96	97.56 ± 12.25	0.96	0.86
Echocardiographic data
EROA, mm²	–	10.46 ± 4.07	22.21 ± 9.26	56.94 ± 17.82	–	<0.0001
RV, ml	–	17.77 ± 7.99	35.83 ± 22.72	87.85 ± 14.93	–	<0.0001
PP, mmHg	–	22.92 ± 4.53	26.43 ± 12.03	33.22 ± 16.12	–	0.11
Risk factors
Hypertension, n (%)	1 (6.25)	5 (22)	5 (24)	7 (35)	0.25	0.37
Diabetes mellitus, n (%)	1 (6.25)	2 (3)	1 (1,5)	0 (0)	0.58	0.39
Smoker, n (%)	5 (31)	1 (4)	6 (30)	3 (15)	0.05	0.03

Data are expressed as the mean ± SD except for sex, echocardiographic data, risk factors where data are expressed in number (per cent)
A: p values between the 4 groups; B: p values between the 3 MR groups
MR mitral regurgitation, HC healthy controls, EROA effective regurgitant orifice area, RV regurgitant volume, PP pulmonary pressure

ISSN: 1559-0275