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Table 1 Changed proteins in mdx-4cv brain tissue as revealed by label-free LC–MS/MS analysis

From: Label-free mass spectrometric analysis reveals complex changes in the brain proteome from the mdx-4cv mouse model of Duchenne muscular dystrophy

Accession number

Protein name

Peptide count

Confidence score

Anova (p)

Fold change

Q91X72

Hemopexin

3

131.20

0.00116

5.64

P29699

Alpha-2-HS-glycoprotein

2

125.19

0.00171

3.47

P22599

Alpha-1-antitrypsin 1-2

2

114.76

0.01445

3.29

P02088

Hemoglobin subunit beta-1

3

260.19

0.00104

3.24

P01942

Hemoglobin subunit alpha

5

370.80

0.00021

3.22

Q00623

Apolipoprotein A-I

8

316.96

0.00522

2.88

P07758

Alpha-1-antitrypsin 1-1

4

108.27

0.01739

2.52

P07724

Serum albumin

16

1174.47

0.00049

2.51

Q923D2

Flavin reductase (NADPH)

3

203.95

0.00171

2.51

Q921I1

Serotransferrin

8

374.58

0.01661

2.18

P03995

Glial fibrillary acidic protein

8

491.51

0.03531

2.00

Q08331

Calretinin

2

94.24

0.04022

1.93

P48036

Annexin A5

2

132.70

0.03204

1.56

P20152

Vimentin

2

213.31

0.00440

1.55

Q9R0P9

Ubiquitin carboxyl-terminal hydrolase isozyme L1

3

165.79

0.02308

1.51

P46460

Vesicle-fusing ATPase

2

134.05

0.00110

1.44

Q9D0E1

Heterogeneous nuclear ribonucleoprotein M

3

63.46

0.01490

1.44

O08788

Dynactin subunit 1

2

126.53

0.01025

1.44

P38647

Stress-70 protein, mitochondrial

6

476.79

0.00175

1.42

P48758

Carbonyl reductase [NADPH] 1

2

119.09

0.01333

1.42

P00920

Carbonic anhydrase 2

2

135.96

0.02814

1.42

P14733

Lamin-B1

2

150.58

0.02918

1.41

Q6IRU5

Clathrin light chain B

2

125.00

0.04203

1.40

Q8R3V5

Endophilin-B2

4

201.90

0.02055

1.39

Q8QZT1

Acetyl-CoA acetyltransferase, mitochondrial

4

215.23

0.00680

1.36

P27773

Protein disulfide-isomerase A3

5

295.10

0.01295

1.35

Q91VR2

ATP synthase subunit gamma, mitochondrial

4

251.82

0.00255

1.35

Q6ZWY9

Histone H2B type 1-C/E/G

2

121.60

0.04212

1.34

Q61171

Peroxiredoxin-2

2

141.40

0.01279

1.33

Q9D051

Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

4

262.12

0.00408

1.32

O35737

Heterogeneous nuclear ribonucleoprotein H

2

100.27

0.01665

1.31

Q03265

ATP synthase subunit alpha, mitochondrial

6

480.06

0.00581

1.30

P20029

78 kDa glucose-regulated protein

2

150.07

0.02510

1.29

Q9QXS6

Drebrin

3

142.38

0.01934

1.28

P62259

14-3-3 protein epsilon

2

103.43

0.02864

1.27

O88737

Protein bassoon

3

215.46

0.01328

1.25

Q811D0

Disks large homolog 1

2

110.76

0.00639

1.25

P14873

Microtubule-associated protein 1B

2

126.07

0.00500

1.24

P16546

Spectrin alpha chain, non-erythrocytic 1

3

197.38

0.01491

1.24

P61264

Syntaxin-1B

4

356.83

0.00121

−1.28

Q02053

Ubiquitin-like modifier-activating enzyme 1

2

131.59

0.04436

−1.41

P51150

Ras-related protein Rab-7a

3

106.89

0.01101

−1.51

P07901

Heat shock protein HSP 90-alpha

2

109.14

0.03836

−1.54

O08599

Syntaxin-binding protein 1

4

315.93

0.01966

−1.54

Q9WV92

Band 4.1-like protein 3

3

218.67

0.00892

−1.90

Q9R0K7

Plasma membrane calcium-transporting ATPase 2

2

108.25

0.01784

−2.77

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Clinical Proteomics

ISSN: 1559-0275