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Fig. 5 | Clinical Proteomics

Fig. 5

From: Mass spectrometry-based analyses showing the effects of secretor and blood group status on salivary N-glycosylation

Fig. 5

Comparison of N-glycosites and glycoproteins by donor and saliva type. Results of analysis of a single secretor and a single nonsecretor are shown. a In total, 160 distinct N-glycosites within 83 glycoproteins were identified. Of those, 79 N-glycosites and 37 glycoproteins were common for both donors vs. species that were unique based on secretor status. b Overall, many more N-glycosites and glycoproteins were detected in the nonsecretor vs. the secretor sample. The majority of N-glycosites observed in the nonsecretor sample were found in parotid saliva while they were more evenly distributed between parotid and SMSL in the secretor sample. Both saliva types shared a large portion of detected N-glycosites. These trends were also observed at the glycoprotein level. c In the donor-common category, more than 60 % of N-glycosites and their parent glycoproteins were observed for both salivas with relatively equal contributions of SMSL and parotid salivas to the remainder. d In the donor-unique category, parotid saliva was the major source of N-glycosites and glycoproteins in both the nonsecretor and the secretor samples

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