Table 1 A partial list of proteins identified that were previously reported
Gene symbol | Protein | Functional role in RA |
|---|---|---|
TIMP1 | Metalloproteinase inhibitor 1 | MMP inhibitor |
C1QA | Complement C1q | Immune response |
MMP9 | Matrixmetalloproteinase 9 | Extracellular matrix (ECM) degradation |
S100A8 | Protein S100A8 | Pannus formation |
PDL2 | Programmed death ligand 2 | Inhibitor of T cell signaling |
NOTCH2 | Neurogenic locus notch homolog protein 2 | Synovial hyperplasia and osteoclastogensis |