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TableĀ 2 A partial list of novel kinases/phosphatases regulated by curcumin

From: Phosphotyrosine profiling of curcumin-induced signaling

Gene symbol Protein Site Phosphopeptide sequence Fold change (curcumin/DMSO)
PTPN6 Tyrosine-protein phosphatase non-receptor type 6 Y536 GQESEyGNITYPPAMK 5.1
ABL2 Abelson tyrosine-protein kinase 2 Y647 yELTGLPEQDR 4.4
INPPL1 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 Y986 NSFNNPAyYVLEGVPHQLLPPEPPSPAR 2.8
MAPK11 Mitogen-activated protein kinase 11 Y182 QADEEMTGyVATR 2.2
PTPRK Receptor-type tyrosine-protein phosphatase kappa Y858 CEGTESPyQTGQLHPAIR 2.5
FRK Fyn-related Src family tyrosine kinase Y497 LEDYFETDSSySDANNFIR 0.5
PEAK1 Pseudopodium enriched atypical kinase 1 Y635 IVINPNAyDNLAIYK 0.5
TNK2 Activated CDC42 kinase 1 Y827 yATPQVIQAPGPR 0.5
AXL Tyrosine-protein kinase receptor UFO Y598 yVLCPSTTPSPAQPADR 0.5
PTPRE Receptor-type tyrosine-protein phosphatase epsilon Y638 VVQDFIDIFSDyANFK 0.5