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Table 1 Proteins selected for development of SRM assays in urine

From: Quantification of angiotensin II-regulated proteins in urine of patients with polycystic and other chronic kidney diseases by selected reaction monitoring

Protein/uniprot ID Uniprot ID Peptide amino acid sequence
Heme oxygenase-1 (HO-1)ab P09601 VQDSAPVETPR TEPELLVAHAYTR
Thrombospondin-1 (TSP-1)ab P07996 TIVTTLQDSIR GGVNDFQGVLQNVR
Glutamate-ammonia ligase(GLUL)a P15104 LTGFHETSNINDFSAGVANR TCLLNETGDEPFQYK LVLCEVFK
Ras homologue family member B (RHOB)ab P62745 LVVVGDGACGK IQAYDYLECSAK
Osteonectin (SPARC)a P09486 YIPPCLDSELTEFPLR FFETCDLDNDK
Transforming growth factor beta, receptor II (TGFBR2)a P37173 LDPTLSVDDLANSGQVGTAR IFPYEEYASWK
Bone marrow stromal cell antigen 1 (BST1)a Q10588 GFFADYEIPNLQK AGLIIPLFLVLASR
Lysophospholipase I (LYPA1)a O75608| ASFPQGPIGGANR LAGVTALSCWLPLR
Laminin, beta 2 (LAMB2)a P55268 LQEGQTLEFLVASVPK GSCYPATGDLLVGR
Drebrin-like (DBNL)ab Q9UJU6 VAGTGEGGLEEMVEELNSGK FQDVGPQAPVGSVYQK
Programmed cell death 4 (PDCD4)b Q53EL6 APQLVGQFIAR SGVPVLAVSLALEGK
Thioredoxin interacting protein (TXNIP)bc Q9H3M7 SFEVVFNDPEK HTYLANGQTK
Pleckstrin-homology like domain, Family A, Member 1(PHLDA1)bc Q8WV24 AAGNGEAEPSGGPSYAGR YMYFTVVMAFGK
Rho/Rac guanine nucleotide exchange factor 2 (ARHGEF2)b Q92974 DLLVGPGVELLLTPR ELLSNVDEGIYQLEK
Hsp40 homologue, Subfamily B, Member 4 (DNAJB4)bc Q9UDY4 IIGYGLPFPK EALCGCSINVPTLDGR
Valosin containing protein (p97)/p47 complex interacting protein (VCPIP1)b Q96JH7 TEPSVFTASSSNSELIR SSGDYSATFLPGLIPAEK
Epidermal growth factor receptor (EGFR)c P00533 EISDGDVIISGNK ELVEPLTPSGEAPNQALLR
RNA binding motif, protein 3 (RBM3)c P98179 YYDSRPGGYGYGYGR GGGDQGYGSGR
  1. Bold peptides were detected and selected for absolute quantification in human urine
  2. aProteins definitively found in urine in prior studies
  3. bProteins previously monitored by SRM in our study
  4. cProteins predicted to be secretory based on computational algorithm (SignalIP)