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Table 2 Correlation filtered 2D DDA/IDA and SWATH protein differences of magnitude greater than 1.59 (threefold up regulating at CPB-1-hour) from both methods marked in (A) and less than −1.59 (threefold down regulating at CPB-1-hour) marked in (B)

From: A proteomic evaluation of urinary changes associated with cardiopulmonary bypass

SWATH

(log2 intensity ratio)

DDA/IDA

(log2 intensity ratio)

UNIPROT entry

Description

(A)

2.53

3.09

P01023

Alpha-2-macroglobulin

1.78

3.53

P04083

Annexin A1

2.05

3.04

P04003

C4b-binding protein alpha chain

3.53

5.73

P00915

Carbonic anhydrase 1

1.82

4.47

P49913

Cathelicidin antimicrobial peptide

1.87

2.36

P36222

Chitinase-3-like protein 1

3.47

4.00

P08123

Collagen alpha-2(I) chain

1.84

2.82

P09871

Complement C1 s subcomponent

1.86

2.01

P02671

Fibrinogen alpha chain

2.37

2.03

P02675

Fibrinogen beta chain

1.76

4.09

P30043

Flavin reductase (NADPH)

1.64

1.84

P00738

Haptoglobin

2.1

1.79

P01860

Ig gamma-3 chain C region

2.09

1.99

P13645

Keratin, type I cytoskeletal 10

2.3

4.12

P02533

Keratin, type I cytoskeletal 14

3.48

6.95

P08779

Keratin, type I cytoskeletal 16

5.44

5.87

Q04695

Keratin, type I cytoskeletal 17

2.17

4.22

P13647

Keratin, type II cytoskeletal 5

2.09

2.79

P02788

Lactotransferrin

3.18

5.10

P14780

Matrix metalloproteinase-9

2.22

2.94

P05164

Myeloperoxidase

2.48

3.59

P05109

Protein S100-A8

(B)

−1.82

−1.94

P02763

Alpha-1-acid glycoprotein 1

−2.35

−2.10

P05090

Apolipoprotein D

−2.14

−3.50

P55287

Cadherin-11

−2.23

−2.87

P19022

Cadherin-2

−1.64

−1.80

P49747

Cartilage oligomeric matrix protein

−2.39

−2.86

P39059

Collagen alpha-1(XV) chain

−1.66

−2.32

P08174

Complement decay-accelerating factor

−1.64

−2.43

Q9HCU0

Endosialin

−1.92

−2.97

P17900

Ganglioside GM2 activator

−3.02

−2.24

Q96RW7

Hemicentin-1

−2.31

−2.30

O75144

ICOS ligand

−2.31

−2.63

Q9BRK3

Matrix-remodeling-associated protein 8

−1.72

−2.20

P08571

Monocyte differentiation antigen CD14

−1.78

−1.62

Q9BXP8

Pappalysin-2

−2.63

−1.72

P0DJD8

Pepsin A-3

−2.16

−1.72

Q6UXB8

Peptidase inhibitor 16

−1.7

−2.24

Q9HCN6

Platelet glycoprotein VI

−1.92

−1.60

P07602

Prosaposin

−1.88

−2.83

Q8WZ75

Roundabout homolog 4

−1.79

−2.70

O00241

Signal-regulatory protein beta-1

−2.02

−3.47

P19320

Vascular cell adhesion protein 1

−2.16

−2.73

Q6EMK4

Vasorin

−1.79

−2.34

Q12907

Vesicular integral-membrane protein VIP36

−2.33

−2.58

Q96DA0

Zymogen granule protein 16 homolog B

  1. These formed the basis for our biological analysis