Fig. 8
From: Mass spectrometry-based approaches to targeted quantitative proteomics in cardiovascular disease
Asbestos-exposed human mesothelin (HM) and malignant mesothelioma (MM) cells release different HMGB1 isoforms. a Representative spectrum of whole protein ESI/MS analysis of HMGB1 in crocidolite asbestos-exposed HM where only nonacetylated HMGB1 was detected. b Representative spectrum of whole protein ESI/MS spectrum of HMGB1 in malignant mesothelioma cells where both hyperacetylated and nonacetylated HMGB1 were detected. Reprinted with permission from [82]